When judging how long you should wait before quitting an internal acne treatment, things can get a bit more complicated, as factors such as your metabolism and body size can effect the treatment. Internal treatments also tend to rely on a great many more active ingredients, and thus can work in a greater variety of ways (or at least attempt to).
I’m not going to cover prescription internal treatments here, and instead focus on the natural acne supplements that are now widely available on the internet. The four main categories are vitamin antioxidants, herbal antioxidants, oil reducers and homeopathic treatments.
I’ll tell you right off the bat that most homeopathic treatments are a waste of time. Homeopathic medicine attempts to cure illnesses by using small amounts of the very ingredients that cause the illness (”fight poison with poison”). There is basically no medical evidence for the success of these treatments, and the amount of homeopathic ingredients used is often too small to make any difference. However, a treatment that calls itself homeopathic may still work if it includes other, more traditional side ingredients. Keep this in mind that many internal treatments will combine a bit of everything, often from all four categories described above.
Both vitamin and herbal antioxidants basically attempt to cure acne in the same fashion: by killing the toxins and bacteria that can build up in your skin cells and pores. Antioxidant treatments tend to be ineffective against moderate-to-severe acne, but may occasionally help in mild cases. With vitamin antioxidants the pathway to treatment is more direct, as the ingredient itself is often absorbed into the bloodstream and plays a direct role in fighting off toxins, both in your skin cells and elsewhere. As such, in most cases you should be able to see noticeable results within 6 weeks, provided that you’re taking an adequate dosage. To maximize your chances of success, it’s often best to take more than the recommended average dosage when starting out. The producers of these products generally expect people to do this, and so the formulas are usually safe at many times the recommended dose. If a treatment contains large amounts of heavy minerals (such as zinc) however, you should probably be more cautious.
Herbal treatments may work in more round-about ways, as their ingredients can need more processing within the body before being ready for use. This can make it difficult to determine a time frame. Many herbs still have had very few medical studies performed on them, and so determining exactly what effects they may have is also difficult. With herbal pills, you shouldn’t give them much longer than vitamins (again, provided you’re taking an adequate dosage). With other herbal remedies though (such as teas), giving them at least 2 months can be a good decision. This can also be easier on you, as drinking green tea for instance is probably easier that downing 6-10 pills a day.
With both vitamin and herbal antioxidant treatments, even if these treatments are not enough alone to tackle your acne, they may still help in small daily doses when taken in addition to another treatment. If you know your diet lacks certain vitamins for instance, supplementing these is generally a good idea.
Treatments that generally work best are those that include heavy amounts of just one or two key ingredients. Internal acne treatments that throw in a little bit of everything are like a grab bag in which the seller is trying to cure acne from every possible angle, but ends up including such weak amounts of each ingredient that none of them are effective at all in the end. If the ingredient list is a mile long, it’s probably a waste of money. This is one of the strengths of oil reducers, in that they tend to rely specifically on a single proven ingredient. These usually take the form of vitamin B5 acne treatments, although derivatives such as pantethine also exist. Vitamin B5 does not work directly as some antioxidants do - as it’s not the B5 that aids in skin oil metabolism, it’s the coenzyme-A that is created using the B5. This factor, in addition to other round-about ways that B5 works (for instance, deriving P. acnes bacteria of their food supply), mean that you’re best off giving B5 treatments at least 2 months before making a definitive call. Although I sell vitamin B5 acne products, I’ll be the first to admit that they don’t work for everyone, and although a small percent do see results after the 2 month mark, in most cases there’s no sense wasting your money if haven’t noticed any improvement by that time.